Trace® General Biomarkers Pipeline
Trace® Companion Diagnostics Pipeline

Pipeline

General Biomarker

Atonomics biomarker program is designed to help monitor indicators of vital organ functions and/or to monitor and detect emerging disease stage

Alanine aminotransferase (ALT) is measured to see if the liver is damaged or diseased. Low levels of ALT are normal, but when the liver is diseased, it releases additional ALT into the bloodstream.

Creatinine is an important indicator of renal health. It is a waste product of muscular metabolism that is normally excreted via the kidneys and if the kidneys are diseased creatinine levels increase.

C-reactive protein (CRP) is an inflammation biomarker. CRP does not locate the inflammation or the condition causing it, but is used together with signs and symptoms to evaluate an individual for acute or chronic inflammatory disease. Tissue injury or infection also causes the CPR level to rise.

D-dimer is a biomarker that helps to detect a venous blood clot (thrombus). The D-dimer test is used to rule out conditions like deep vein thrombosis or pulmonary embolism. D-dimer is also used when clinicians suspect aortic dissection or conditions causing hypercoagulability (a tendency to clot inappropriately) as e.g. disseminated intravascular coagulation (DIC).

Plasma glucose Plasma glucose is a key tool for diabetes monitoring. Blood glucose meters measures glucose in whole blood, which represents a problem in relation to haematocrit values of individuals. trace® measures glucose after filtration from whole blood to plasma thereby circumventing the haematocrit problem.

1,5-Anhydroglucitol assay (1,5-AG) can be used to identify glycaemic variability in people with diabetes who have normal or near normal HbA1c levels. Monitoring 1,5-AG in people with either type-1 or type-2 diabetes can be used to determine if blood glucose levels are frequently above 180 mg/dL, even in the presence of relatively good HbA1c or blood glucose levels. There are data indicating that the 1,5-AG is useful to fill the gap and offer complementary information to HbA1c and fructosamine tests.

Glycated albumin is a glycaemic indicator and has the potential to become an intermediate-term (2-3 weeks) glycaemic test that fills the gap between self-monitoring of blood glucose and haemoglobin A1c (HbA1c) in improving overall diabetes management.

Total IgE can be used to screen for and detect allergic diseases. It’s a pre-screen marker before the allergen-specific-IgE test and/or the skin prick test is performed at the GP office.

Premium Trace®

Premium Trace® General Biomarkers Pipeline
Premium Trace® is Trace® including a proprietary chemistry allowing for high sensitivity applications using micro-photomultiplier (microPMT).

B-type Natriuretic Peptide (BNP) is a biomarker for simple and objective measures of cardiac function. Since its discovery over 20 years ago, BNP has emerged as an important biomarker for minor myocardial damage with an established role in the diagnosis of Congestive Heart Failure (CHF).

Thyroid-stimulating Hormone (TSH) is the test of choice for screening thyroid function and is used together with clinical symptoms of thyroid disease to monitor hyper- or hypothyroidism.

Vitamin D test determines any vitamin D deficiency; if you are receiving vitamin D supplements, the test determines over- or under prescription.